Friday, 25 April 2014

Reasons In Vitro Fertilization (IVF) Fails to Result in Pregnancy

The bitter truth behind a botched IVF cycle is – as advanced as fertility treatments are, the question about failure might not always have an answer!

When the embryos looked perfect, uterine lining looked great, and everything went according to prescription, then it is difficult accept the failure of IVF cycle.

Below are the reasons why sometimes In Vitro Fertilization doesn't work –

The embryos didn't implant

When the development of embryos stops prior to reaching implantation stage then uterine lining may possibly reject the embryo and the implantation fails. Women, in their mid 30s, who undergo IVF after detection of infertility, are more likely to encounter this situation. However, the cessation of embryo development is thought to be the most common cause of lack of pregnancy at any age, and in fact, even during natural conception. A woman’s age affects her chances of getting pregnant, whether or not infertility treatments are involved.

The embryos started to implant…and then stopped

If the embryos have abnormal chromosomes, they won’t implant. The only way to tell whether embryos have the right chromosomes is to do Pre-implantation Genetic Diagnosis (PGD), a procedure in which one cell is removed from the embryo before implantation and its DNA is analyzed for abnormalities.
Although this is an expensive medical procedure, it only checks the abnormalities and does improve overall pregnancy rates.

The embryos were damaged, so the IVF didn't work

The damage, either during the embryos’ growth in the lab or the transfer to the uterus might result in implantation failure. Like I have always said, the IVF is performed part by doctors and part by human body. From simulation to egg formation, retrieval to embryo formation, embryo transfer to implantation, IVF is requires both the efforts of doctor and response of the female’s body to the effort. Occasionally, the embryo does not grow as intended, which might damage the embryo.  

There is a problem with your uterus

If the uterine lining is not healthy or ready for the implantation, then there are chances your IVF would not work. Fibroids, polyps, or polycystic ovarian syndrome can make getting pregnant more difficult. Sadly, there are no ways to test the endometrium or uterine lining during the actual cycle because a biopsy might prevent implantation.

The embryo transfer process went poorly

If a woman experiences bleeding or cramping (or both) during the in vitro fertilization procedure, the chances of getting pregnant are considerably decreased. The uterus cramps, the embryos are displaced and become less capable to be implanted, as a result the IVF cycle fails.

Sometimes, patients blame the doctors. It is understandable because one might not want to expense of money and time without results. But, even though the infertility treatment is one of the most advanced medical procedures but sadly there are arenas which are yet to be discovered, like the prevention of implantation failure. You need to be positive and have faith on your doctor.

Dr Neeraj Pahlajani

1 comment:

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